Donald L. Heald: search on Z-Library

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1

The effects of gastric pH and food on the pharmacokinetics of a new oral cephalosporin, cefpodoxime proxetil

Hughes, George S, Heald, Donald L, Barker, Kerry B, Patel, Rajendra K, Spillers, Carol R, Watts, Kathy C, Batts, Donald H, Euler, Arthur R

Journal:

Clinical Pharmacology & Therapeutics

Year:

1989

Language:

english

File:

PDF, 993 KB

english, 1989

2

From preclinical to human – prediction of oral absorption and drug–drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example

Vikash Kumar Sinha, Jan Snoeys, Nancy Van Osselaer, Achiel Van Peer, Claire Mackie, Donald Heald

Journal:

Biopharmaceutics & Drug Disposition

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

3

Best practices for the use of itraconazole as a replacement for ketoconazole in drug-drug interaction studies

Liu, Lichuan, Bello, Akintunde, Dresser, Mark J., Heald, Donald, Komjathy, Steven Ferenc, O'Mara, Edward, Rogge, Mark, Stoch, S. Aubrey, Robertson, Sarah M.

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 250 KB

english, 2016

4

Development of a Target cell-Biologics-Effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents

Jiang, Xiling, Chen, Xi, Carpenter, Thomas J., Wang, Jun, Zhou, Rebecca, Davis, Hugh M., Heald, Donald L., Wang, Weirong

Journal:

Year:

2018

Language:

english

File:

PDF, 2.77 MB

english, 2018

5

Imaging studies of biodistribution and kinetics in drug development

Marc S. Berridge, Donald L. Heald, Zhenghong Lee

Journal:

Drug Development Research

Year:

2003

Language:

english

File:

PDF, 242 KB

english, 2003

6

Mapping PET-measured triamcinolone acetonide (TAA) aerosol distribution into deposition by airway generation

Zhenghong Lee, Marc S Berridge, Warren H Finlay, Donald L Heald

Journal:

International Journal of Pharmaceutics

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

7

Standard reporting requirements for biological samples in metabolomics experiments: mammalian/in

Julian L. Griffin, Andrew W. Nicholls, Clare A. Daykin, Sarah Heald, Hector C. Keun, Ina Schuppe-Koistinen, John R. Griffiths, Leo L. Cheng, Philippe Rocca-Serra, Denis V. Rubtsov, Donald Robertson

Journal:

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

8

Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent

Uday R. Khire, Donald Bankston, James Barbosa, David R. Brittelli, Yolanda Caringal, Robert Carlson, Jacques Dumas, Todd Gane, Sarah L. Heald, Barbara Hibner, Jeffrey S. Johnson, Michael E. Katz, Nanc

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 178 KB

english, 2004

9

Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation

Ian R. Wilding, Stanley S. Davis, Robert A. Sparrow, John A. Ziemniak, Donald L. Heald

Journal:

Journal of Controlled Release

Year:

1995

Language:

english

File:

PDF, 629 KB

english, 1995

10

Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation: Journal of Controlled Release, 33 (1995) 89–97

Ian R. Wilding, Stanley S. Davis, Robert A. Sparrow, John A. Ziemniak, Donald L. Heald

Journal:

Journal of Controlled Release

Year:

1995

Language:

english

File:

PDF, 38 KB

english, 1995

11

The Effect of Scatter and Attenuation on Aerosol Deposition as Determined by Gamma Scintigraphy

Lee, Zhenghong, Berridge, Marc S., Nelson, A. Dennis, Heald, Donald L.

Journal:

Journal of Aerosol Medicine

Year:

2001

Language:

english

File:

PDF, 334 KB

english, 2001

12

The pharmacokinetics and gastrointestinal transit of Cormax once-a-day

Heald, Donald L

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1992

Language:

english

File:

PDF, 217 KB

english, 1992

13

A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION

ARGENTI, DOMENICK, IRELAND, DENISE, HEALD, DONALD L.

Journal:

The Journal of Urology

Year:

2001

Language:

english

File:

PDF, 79 KB

english, 2001

14

Pharmacokinetics of topiramate in patients with renal impairment, end-stage renal disease undergoing hemodialysis, or hepatic impairment

Manitpisitkul, Prasarn, Curtin, Christopher R., Shalayda, Kevin, Wang, Shean-Sheng, Ford, Lisa, Heald, Donald L.

Journal:

Epilepsy Research

Year:

2014

Language:

english

File:

PDF, 904 KB

english, 2014

15

Mechanistic Understanding of Brain Drug Disposition to Optimize the Selection of Potential Neurotherapeutics in Drug Discovery

Loryan, Irena, Sinha, Vikash, Mackie, Claire, Peer, Achiel, Drinkenburg, Wilhelmus, Vermeulen, An, Morrison, Denise, Monshouwer, Mario, Heald, Donald, Hammarlund-Udenaes, Margareta

Journal:

Pharmaceutical Research

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

16

A Mass Balance Study to Evaluate the Biotransformation and Excretion of [ 14 C]-Triamcinolone Acetonide following Oral Administration

Argenti, Domenick, Jensen, Bradford K., Hensel, Russell, Bordeaux, Kirk, Schleimer, Robert, Bickel, Carol, Heald, Donald

Journal:

Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 186 KB

english, 2000

17

BOOK REVIEWS

Waltonen, Karma, Weinstein, Norman, Masterson, Donald, Gauthier, Jennifer L., Tomhave, Jonathan S., Broadway, Michael J., Chapnick, Adam, Brégent-Heald, Dominique, Payne, Brian J., Rempel, Gerhard, Ch

Journal:

The American Review of Canadian Studies

Year:

2006

Language:

english

File:

PDF, 2.91 MB

english, 2006

18

Pharmacokinetic interactions between topiramate and pioglitazone and metformin

Manitpisitkul, Prasarn, Curtin, Christopher R., Shalayda, Kevin, Wang, Shean-Sheng, Ford, Lisa, Heald, Donald

Journal:

Epilepsy Research

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

19

Regional Distribution and Kinetics of Inhaled Pharmaceuticals

Berridge, Marc, Lee, Zhenghong, Heald, Donald

Journal:

Current Pharmaceutical Design

Year:

2000

Language:

english

File:

PDF, 325 KB

english, 2000

20

[IEEE 2012 SC - International Conference for High Performance Computing, Networking, Storage and Analysis - Salt Lake City, UT, USA (2012.11.10-2012.11.16)] 2012 International Conference for High Performance Computing, Networking, Storage and Analysis - Demonstrating Lustre over a 100Gbps wide area network of 3,500km

Henschel, Robert, Simms, Stephen, Hancock, David, Michael, Scott, Johnson, Tom, Heald, Nathan, William, Thomas, Berry, Donald, Allen, Matt, Knepper, Richard, Davy, Matthew, Link, Matthew, Stewart, Cra

Year:

2012

Language:

english

File:

PDF, 953 KB

english, 2012

21

Pharmacokinetic interactions between topiramate and diltiazem, hydrochlorothiazide, or propranolol

Manitpisitkul, Prasarn, Curtin, Christopher R., Shalayda, Kevin, Wang, Shean-Sheng, Ford, Lisa, Heald, Donald

Journal:

Clinical Pharmacology in Drug Development

Year:

2014

Language:

english

File:

PDF, 172 KB

english, 2014

22

Molecular Properties Determining Unbound Intracellular and Extracellular Brain Exposure of CNS Drug Candidates

Loryan, Irena, Sinha, Vikash, Mackie, Claire, Van Peer, Achiel, Drinkenburg, Wilhelmus H., Vermeulen, An, Heald, Donald, Hammarlund-Udenaes, Margareta, Wassvik, Carola M.

Journal:

Molecular Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 1.81 MB

english, 2015

23

A Pharmacokinetic Study to Evaluate the Absolute Bioavailability of Triamcinolone Acetonide following Inhalation Administration

Argenti, Domenick, Shah, Bharti, Heald, Donald

Journal:

Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

24

Visualization of Product Performance in the Gut: What Role in the Drug Development/Regulatory Paradigm?

Wilding, Ian R., Heald, Donald L.

Journal:

Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

25

Pharmacokinetics of Enoxaparin in Patients Undergoing Percutaneous Coronary Intervention With and Without Glycoprotein IIb/IIIa Therapy

Argenti, Domenick, Hoppensteadt, Debra, Heald, Donald, Jensen, Brad, Fareed, Jaweed

Journal:

American Journal of Therapeutics

Year:

2003

Language:

english

File:

PDF, 306 KB

english, 2003

26

In Vivo Characterization of Inhaled Pharmaceuticals Using Quantitative Positron Emission Tomography

Berridge, Marc S., Heald, Donald L.

Journal:

Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 52 KB

english, 1999

27

THE EFFECT OF FOOD ON THE BIOAVAILABILITY OF EBASTINE

Pentikis, Helen Stamidis, Huang, Mei-Ying, Dorr, Mary Beth, Heald, Donald L.

Journal:

American Journal of Therapeutics

Year:

1997

File:

PDF, 417 KB

1997

28

Nasal Mucosal Inflammation Has No Effect on the Absorption of Intranasal Triamcinolone Acetonide

Argenti, Domenick, Colligon, Irina, Heald, Donald, Ziemniak, John

Journal:

Journal of Clinical Pharmacology

Year:

1994

Language:

english

File:

PDF, 796 KB

english, 1994

29

Clinical pharmacology, creating current and future success in drug development

Rogge, Mark C., Dresser, Mark, Fossler, Michael, Heald, Donald, Stoch, S. Aubrey, Vanevski, Konstantina M., Bello, Akintunde

Journal:

Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 133 KB

english, 2015

30

COMPARATIVE PHARMACOKINETICS AND BIOAVAILABILITY OF DILACOR XR AND CARDIZEM CD IN HEALTHY VOLUNTEERS

Argenti, Domenick, Huang, Mei-Ying, Heald, Donald, Ziemniak, John

Journal:

American Journal of Therapeutics

Year:

1995

File:

PDF, 764 KB

1995

31

Uptake and Distribution of Lidocaine in Fetal Lambs

Kennedy, Roland L., Bell, John U., Miller, Richard P., Doshi, Dinesh, de Sousa, Hansel, Kennedy, Matthew J., Heald, Donald L., Bettinger, Robert, David, Yadin

Journal:

Year:

1990

File:

PDF, 495 KB

1990

32

THE PHARMACOKINETICS AND PHARMACODYNAMICS OF DESMOPRESSIN

Argenti, Domenick, Jensen, Bradford K., Heald, Donald

Journal:

American Journal of Therapeutics

Year:

1997

File:

PDF, 500 KB

1997

33

THE PHARMACOKINETICS OF ONCE-DAILY DILTIAZEM SR (SUSTAINED-RELEASE) IN YOUNG VERSUS ELDERLY HYPERTENSIVE PATIENTS

Argenti, Domenick, Huang, Mei-Ying, Heald, Donald, Ziemniak, John

Journal:

American Journal of Therapeutics

Year:

1994

File:

PDF, 552 KB

1994

34

A Study Comparing the Clinical Pharmacokinetics, Pharmacodynamics, and Tolerability of Triamcinolone Acetonide HFA-134a Metered-Dose Inhaler and Budesonide Dry-Powder Inhaler following Inhalation Administration

Argenti, Domenick, Shah, Bharti, Heald, Donald

Journal:

Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 1.79 MB

english, 2000

35

Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques

Warren, Travis K., Whitehouse, Chris A., Wells, Jay, Welch, Lisa, Charleston, Jay S., Heald, Alison, Nichols, Donald K., Mattix, Marc E., Palacios, Gustavo, Kugleman, Jeffrey R., Iversen, Patrick L.,

Journal:

PLoS Neglected Tropical Diseases

Year:

2016

Language:

english

File:

PDF, 4.62 MB

english, 2016

36

Can Incense-Cedar Be Managed for Birds?

Morrison, Michael L., Heald, Robert C., Dahlsten, Donald L.

Journal:

Western Journal of Applied Forestry

Year:

1990

Language:

english

File:

PDF, 136 KB

english, 1990

37

Geriatrics 2030: Developing Drugs to Care for Older Persons—A Neglected and Growing Population

Lau, S.W. Johnny, Schlender, Jan‐Frederik, Slattum, Patricia W., Heald, Donald L., O'Connor‐Semmes, Robin

Journal:

Clinical Pharmacology & Therapeutics

Year:

2019

Language:

english

File:

PDF, 396 KB

english, 2019

38

Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Singh, Aman P., Zheng, Xirong, Lin-Schmidt, Xiefan, Chen, Wenbo, Carpenter, Thomas J., Zong, Alice, Wang, Weirong, Heald, Donald L.

Journal:

Year:

2020

Language:

english

File:

PDF, 6.84 MB

english, 2020

39

Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Singh, Aman P., Zheng, Xirong, Lin-Schmidt, Xiefan, Chen, Wenbo, Carpenter, Thomas J., Zong, Alice, Wang, Weirong, Heald, Donald L.

Journal:

Year:

2020

File:

PDF, 6.84 MB

2020

40

Modelâbased Cellular Kinetic Analysis of Chimeric Antigen ReceptorâT Cells in Humans

Liu, Can, Ayyar, Vivaswath S., Zheng, Xirong, Chen, Wenbo, Zheng, Songmao, Mody, Hardik, Wang, Weirong, Heald, Donald, Singh, Aman P., Cao, Yanguang

Journal:

Clinical Pharmacology & Therapeutics

Year:

2020

File:

PDF, 12.68 MB

2020